New Delhi, Nov 30
SARS-CoV-2, the virus behind the Covid-19 pandemic, remains in the skull and meninges for years after infection, leading to a long-lasting effect on the brain, according to a major German study.
Researchers from Helmholtz Munich and Ludwig-Maximilians-Universitat (LMU) found that SARS-CoV-2 spike protein remains in the brain's protective layers -- the meninges, and the skull's bone marrow for up to four years after infection.
These spike proteins are responsible for triggering chronic inflammation in affected individuals and increase the risk of neurodegenerative diseases, the team found.
Prof. Ali Ertürk, Director at the Institute for Intelligent Biotechnologies at Helmholtz Munich said that the long-term neurological effects include “accelerated brain ageing, potentially leading to a loss of five to 10 years of healthy brain function in affected individuals."
The study, published in the journal Cell Host & Microbe, may also have neurological symptoms of long Covid such as headaches, sleep disturbances, and “brain fog,” or cognitive impairment.