Overview

Overworked brain cells may burn out in Parkinson's disease: Study

Overworked brain cells may burn out in Parkinson's disease: Study

Scientists have showed that when brain cells are constantly overactivated for weeks on end, they degenerate and ultimately die, a finding that may help explain what goes awry in the brains of people with Parkinson's disease.

Researchers have long known that a particular subset of neurons dies as Parkinson's disease progresses, but they weren't sure why.

The new study, published in the journal eLife, shows that in mice, chronic activation of these neurons can directly cause their demise.

The scientists hypothesise that in Parkinson's, neuron overactivation could be triggered by a combination of genetic factors, environmental toxins, and the need to compensate for other neurons that are lost.

"An overarching question in the Parkinson's research field has been why the cells that are most vulnerable to the disease die," said Ken Nakamura, investigator at Gladstone Institutes in the US.

GST reforms may offset tariff impact, India remains fastest-growing economy: Fitch Solutions' BMI

GST reforms may offset tariff impact, India remains fastest-growing economy: Fitch Solutions' BMI

The upcoming Goods and Services Tax (GST) reforms, which aim to cut rates and boost private consumption, could offset the US tariff impact, BMI, a Fitch Solutions company, said on Thursday, adding that India is likely to remain one of the fastest-growing emerging market economies in Asia through this decade.

India's GDP is projected to hold above 6 per cent, even as additional US tariffs hit certain industries, according to the note by BMI.

"We forecast India's economic growth to steadily slow to just above 6.0 per cent by the decade's end, slightly below the 2010-2019 pre-pandemic average of 6.5 per cent, yet still positioning India among Asia's fastest-growing economies," BMI said.

It further stated that productivity is projected to grow around 5 per cent over the coming decade, providing substantial momentum to GDP growth.

Two from MP's Mandsaur die in Vaishno Devi landslide

Two from MP's Mandsaur die in Vaishno Devi landslide

Two people from Madhya Pradesh's Mandsaur were killed in the Vaishno Devi landslide in Jammu and Kashmir.

According to information, a group of people from Bhilkhedi village in Mandsaur district had gone to Vaishno Devi.

A team of senior officials from the district administration visited to Bhilkhedi village and met the family members. Those who died in the tragic landslide have been identified as Fakirchand Gurjar (50) and Ratan Bai (65).

Two people from the area were injured in the incident and have been identified as Sohan Bai (47) and Devilal (45).

Two people still missing from the area were identified as Parmanand (29) and Arjun (25).

Akshay Oberoi wraps up ‘Sunny Sanskari Ki Tulsi Kumari’ shoot

Akshay Oberoi wraps up ‘Sunny Sanskari Ki Tulsi Kumari’ shoot

Actor Akshay Oberoi has officially wrapped up his part in the upcoming family entertainer Sunny Sanskari Ki Tulsi Kumari and said that it has been an “incredibly fulfilling experience.”

Akshay shared a heartwarming video from the wrap-up party.

The video shows Akshay in stylish party wear, warmly hugging his co-stars Janhvi Kapoor, Varun Dhawan, Rohit Saraf, and others. There are also a few glimpses from the poster shoot of the film.

For the caption, he wrote: “Dharma Movies are always known for celebrating families and the bonds between them. This was my first time working with the company, and I can honestly say, that’s exactly how the shoot felt—full of love, magic, and laughter. Here’s some #BTS that captures that same family fun. Thank you for the journey! @shashankkhaitan @karanjohar @dharmamovies.”

Kane strikes late as Bayern edge Wiesbaden in German Cup opener

Kane strikes late as Bayern edge Wiesbaden in German Cup opener

Harry Kane once again showed his striker's instinct, netting twice including a dramatic stoppage-time winner, as Bayern Munich scraped past third-tier Wehen Wiesbaden 3-2 in the first round of the German Cup on Wednesday night.

Fielding a rotated side, Bayern made a flying start. Within seconds of kick-off, Luis Diaz tested Florian Stritzel in the Wiesbaden goal, who would go on to deliver a string of fine saves. The early breakthrough arrived after a foul on Sacha Boey, with Kane converting coolly from the penalty spot in the 16th minute.

Short spell of rain lashes Gujarat

Short spell of rain lashes Gujarat

A short spell of rainfall lashed several parts of Gujarat on Thursday, with Panchmahal recording the highest.

According to data from the State Emergency Operation Centre, Gandhinagar, Morwa (Hadaf) taluka in Panchmahal received 20 mm (0.79 inch) rainfall, the highest in the state during the two-hour period, 6 a.m. to 8 a.m.

Surat's Umarpada received 17 mm (0.67 inch) of rain, while Idar in Sabarkantha received 13 mm (0.51 inch).

Other areas, including Kamrej (9 mm), Olpad (8 mm), Valia in Bharuch (7 mm), and Himatnagar in Sabarkantha (4 mm), also recorded measurable showers.

South Korea: Yoon absent from his insurrection trial for 6th consecutive time

South Korea: Yoon absent from his insurrection trial for 6th consecutive time

Former South Korean President Yoon Suk Yeol was absent from his insurrection trial for the sixth consecutive time on Thursday, leading the court to proceed without him.

Yoon has refused to appear for his trial at the Seoul Central District Court since his second arrest on July 10, citing health issues.

The bench opened Thursday's hearing by noting the defendant was absent again and that the detention centre where Yoon is jailed had sent a note explaining the difficulty of bringing him by force.

Heavy rain wreaks havoc in Rajasthan; schools, colleges closed in Jodhpur today

Heavy rain wreaks havoc in Rajasthan; schools, colleges closed in Jodhpur today

In view of heavy rainfall and waterlogging in Jodhpur, the district administration has declared a holiday for students in all educational institutions, including schools and colleges, on Thursday.

District Collector Gaurav Agarwal issued the order late Wednesday under Sections 30 and 34 of the Disaster Management Act 2005.

The decision follows heavy rainfall on August 27, which caused severe waterlogging in several areas.

According to the Meteorological Department, moderate to heavy rainfall is also expected in the coming hours, which could further aggravate the situation.

Delhi Police nab two US-based Harry Boxer gang members

Delhi Police nab two US-based Harry Boxer gang members

Two members of the US-based Harry Boxer gang were arrested following a late-night encounter with the Special Cell of the Delhi Police in the New Ashok Nagar area of the national capital, officials said on Thursday.

Acting on intelligence inputs about their movement, the Special Cell laid a trap to intercept the suspects. However, when the police team attempted to stop them, the duo opened fire.

In retaliatory action, one of the accused was shot in the leg before both were overpowered and taken into custody.

According to sources, the arrested men have been identified as Kartik Jakhar and Kavish, both of whom work for US-based gangster Harry Boxer, who has more than half a dozen criminal cases registered against him.

This encounter came shortly after police arrested three men and apprehended a juvenile in connection with a firing incident in East Vinod Nagar linked to a financial dispute.

Adani Portfolio EBITDA crosses Rs 90,000 crore for 1st time, Q1 EBITDA at record high

Adani Portfolio EBITDA crosses Rs 90,000 crore for 1st time, Q1 EBITDA at record high

The Adani Portfolio EBITDA reached Rs 90,572 crore on a trailing 12-month basis for the first time -- up 10 per cent year-on-year -- with Q1 FY26 EBITDA also reaching a record high at Rs 23,793 crore, the Adani Group said on Thursday.

Core infrastructure businesses (utility, transport, and incubating infra businesses under Adani Enterprises) accounted for 87 per cent of total EBITDA in Q1 FY26.

"Incubating Infra assets (airports, solar and wind manufacturing, and roads) crossed Rs 10,000 crore EBITDA for the first time,” the Adani Group said in a statement.

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